Lipids and Lipid Derivatives
Chem-Impex International, Inc. Linolenic acid | 463-40-1 | MFCD00065720 | 1G
Linolenic acid, 463-40-1, MFCD00065720, 1G
Cayman Chemical Palmitic Acid-13C (C1, C2, C3, and C4 labeled), Purity: ≥98%, CAS: 287100-89-4, 100 mg
An internal standard for the quantification of palmitic acid by GC- or LC-MS
Selleck Chemical LLC Palmitoleic acid S3341-25mg
Palmitoleic acid (POA Palmitoleate) stimulates the uptake of glucose in liver through activation of AMPK and FGF-21 dependent on PPAR
Medchemexpress LLC Palmitic acid-1,2,3,4-13C4 | 287100-89-4 | 260.39 | 25 MG
Palmitic acid-1,2,3,4-13C4 is the 13C-labeled Palmitic acid, a long-chain saturated fatty acid found in animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. It is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Revvity Health Sciences Inc Oleic Acid, [9,10-<sup>3</sup>H(N)]-, 5mCi (185MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502811002.jpg-250.jpg)
Revvity Health Sciences Inc Oleic Acid, [9,10-3H(N)]-, 5mCi (185MBq)
Oleic Acid, [9,10-3H(N)]-, 5mCi (185MBq)
Cayman Chemical Palmitic Acid-d9, Purity: ≥99% deuterated forms (d1-d9), CAS: 1173022-49-5, 1 mg
An internal standard for the quantification of palmitic acid by GC- or LC-MS
Medchemexpress LLC Eicosapentaenoic acid | 10417-94-4 | 99.86% | 302.45 | 1 G
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). It exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). This compound activates the RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells and can promote relaxation of vascular smooth muscle cells and vasodilation.
- Orally active Omega-3 long-chain polyunsaturated fatty acid
- Exhibits DNA demethylating action
- Promotes re-expression of tumor suppressor gene
- Activates RAS/ERK/C/EBPβ pathway
- Promotes relaxation of vascular smooth muscle cells and vasodilation
Cambridge Isotope Laboratories cis-5 8 11 14 17-Eicosapentaenoic acid (unlabeled) 1 mg
cis-5 8 11 14 17-Eicosapentaenoic acid (unlabeled) 1 mg
Cayman Chemical Docetaxel-d9 500ug
An internal standard for the quantification of docetaxel by GC- or LC-MS
Medchemexpress LLC Docetaxel | 114977-28-5 | 99.9% | C43H53NO14 | 1 G
Docetaxel is a microtubule depolymerization inhibitor with an IC50 of 0.2 μM. It attenuates the effects of bcl-2 and bcl-xL gene expression, arrests the cell cycle at G2/M, and leads to cell apoptosis. Docetaxel exhibits anti-cancer activity.
- Microtubule depolymerization inhibitor
- Attenuates bcl-2 and bcl-xL gene expression
- Arrests cell cycle at G2/M
- Leads to cell apoptosis
- Exhibits anti-cancer activity
Cayman Chemical 10-acetyl Docetaxel, Purity: ≥98%, CAS: 125354-16-7, 100 mg
A derivative of paclitaxel and an inhibitor of microtubule depolymerization; inhibits calcium-induced depolymerization of calf brain MTP in a cell-free assay at 20 µM; cytotoxic to J774.2 cells (EC50 = 0.05 µM)
Cayman Chemical Paclitaxel, Purity: ≥98%, CAS: 33069-62-4, 100 mg
A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms
Cayman Chemical 7-epi Paclitaxel, Purity: ≥98%, CAS: 105454-04-4, 10 mg
An active metabolite of paclitaxel; exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization
AdipoGen Docetaxel
Chemical. CAS 114977-28-5. Formula C43H53NO14. MW 807.88. Synthetic. Anticancer agent. Semisynthetic analog of taxol paclitaxel. Inhibits microtubule disassembly and inhibits cell replication. Binds to and stabilizes the beta−tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest at G2/M and apoptosis. This cytotoxic activity has been widely exploited in suppressing oncogenic proliferation. Displays potent and broad antineoplastic properties, used mainly for the treatment of breast, ovarian, and non-small cell lung cancer. Also inhibits pro-angiogenic factors such as vascular endothelial growth factor VEGF and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Also studied for use as a radiation-sensitizing agent.
Medchemexpress LLC Docetaxel Standard | 114977-28-5 | C43H53NO14 | 25MG
Docetaxel (RP-56976) is a microtubule depolymerization inhibitor with an IC50 of 0.2 μM. It attenuates the effects of bcl-2 and bcl-xL gene expression, arrests the cell cycle at G2/M, and leads to cell apoptosis. Docetaxel exhibits anti-cancer activity.
- Microtubule depolymerization inhibitor
- Attenuates bcl-2 and bcl-xL gene expression
- Arrests cell cycle at G2/M
- Leads to cell apoptosis
- Exhibits anti-cancer activity